Reduced Heart Rate Variability as A Risk Factor for Cardiovascular Disease in Young Healthy Adults with Low and High Body Mass Indexes – A Descriptive Study

Background: Heart rate variability (HRV) is a used to assess autonomic nervous system input to the heart. Studies on the impact of HRV on underweight are limited. Aims/Objectives: To evaluate HRV in age matched young adults of different BMI category. Methodology: This cross-sectional study was done among healthy young adult volunteers between 18 and 25 years of age. Anthropometric variables were measured. ECG was recorded in lead II configuration for 5 minutes. Heart rate variability was analysed with Kubios HRV analyzer. Results: HRV indices were reduced in underweight (UW), overweight (OW) and obese group compared to normal weight (NW) BMI group. Second order polynomial regression between BMI and HF log power in both genders shows an inverted U-shaped relationship with BMI. The association between BMI, waist circumference and body fat (percentage) with HRV indices shows a significant relation to heart rate var-iability among which waist circumference (WC) shows a greater association with HRV indices than BMI. Comparison of HRV parameters among men and women of different BMI group shows female had great-er heart rate variability compared to males across BMI Conclusions: underweight individual also have increased cardiovascular risk like obese group and ab-dominal obesity is better indicator of cardiovascular risk than BMI.

Angiographic Profile Of Coronary Artery Disease In Women Undergoing Coronary Angiography In A Tertiary Care Hospital

BACKGROUND: Cardiovascular disease still remains the leading cause of death in women. The clinical and angiographic profiles of women undergoing CAG must be clearly understood. However there is not much data regarding the angiographic pattern of CAD in women undergoing CAG. AIM: Our aim was to study the angiographic pattern of coronary artery disease in women undergoing coronary angiogram in our institute. METHODS: The records of 275 consecutive female patients who underwent CAG in our institute from December 2017 to May 2018 were retrospectively analysed. The clinical and angiographic data were taken for detailed analysis from CAG reports and discharge summaries. Baseline characteristics of patients were noted. Angiographic pattern was analysed. All statistical analysis was performed using SPSS17 software. Ap-value <0.05 was considered statistically significant. RESULTS: In our study group, LAD was the most commonly involved vessel, followed by RCA and LCX respectively.26.91% had normal epicardial coronaries. 9.82% had minimal CAD. 28% had SVD;16.36% had DVD; 15.63% had TVD;21.8% had branch vessel disease. In our study, 7.63% had LMD.1.82% had coronary artery anomalies in the form of abnormal origin. In our study, the prevalence of multi vessel disease (DVD and TVD) is 32% among women undergoing CAG. CONCLUSION: There is a significant increase in the number of women diagnosed to have CAD. Understanding the angiographic pattern of CAD in women will give further insight towards aggressive coronary interventions in women.